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  • Videonystagmograph

    Categories:

    Product Catalogu

    Number of downloads:

    2

    File size:

    2.4M

    Time:

    2019-10-28 15:58:00

  • Auditory

    Auditory evoked potentiometer

    Thepurposeofthisstudywastoobservetheototoxiceffectsofkanamycinsulfate(KM)onadultrats.FortymaleSprague-Dawley(SD)ratsaged6to7weekswererandomlydividedintotwogroups:theexperimentalgroup,intraperitonealinjectionofKM(500mg/kg)for2weekseachday:thecontrolgroup,injectionofthesameamountofnormalsalinefor2weeks.Theauditorybrainstemresponse(ABR)wasmeasuredtoobservethehearingchangesinrats.AftertheABRtestwascompleted,thecochleawasisolatedforbasementmembranesmearandcochlearfrozensection,andthedensityandcochlearmorphologyofspiralganglioncells(SGCs)wereobserved.Theresultsshowedthatafter2weeksofKMinjection,theauditorythresholdsofratsineachfrequencyincreasedsignificantly,andtheincreaserangewasmorethan60dB.Overtime,thedensityofSGCsintheKMgroupgraduallydecreased,andthestructureoftheCortiorganremained,buttheouterhairBothcellsandinnerhaircellsweredeletedtovaryingdegrees,withouterhaircellsbeingevenworse;innerhaircelldeletionwasparalleltothedecreaseindensityofSGCs.Theaboveresultsindicatethat,after6weeksofKMeffectin6-7weekoldrats,hearingwillbesignificantlyreduced,andseveredeafnessorevendeafnesswillbeachieved.OtotoxicityofKMiscloselyrelatedtothedamageofSGCsandinnerandouterhaircells.

    Categories:

    Product Catalogu

    Number of downloads:

    4

    File size:

    2.9M

    Time:

    2019-08-27 11:42:00

  • Otoacoustic

    Categories:

    Product Catalogu

    Number of downloads:

    0

    File size:

    1.2M

    Time:

    2019-11-08 15:27:00

  • Jarno

    Categories:

    Product Catalogu

    Number of downloads:

    0

    File size:

    2.6M

    Time:

    2019-11-08 15:21:00

  • Bell

    Categories:

    Product Catalogu

    Number of downloads:

    0

    File size:

    2.2M

    Time:

    2019-11-06 22:01:00

  • Middle

    Categories:

    Product Catalogu

    Number of downloads:

    0

    File size:

    2.0M

    Time:

    2019-11-06 21:59:00

Categories:
Product Catalogu
File size:
2.4M
Number of downloads:
2
2019-10-28 15:58:00
Categories:
Product Catalogu
File size:
2.9M
Number of downloads:
4
2019-08-27 11:42:00
Thepurposeofthisstudywastoobservetheototoxiceffectsofkanamycinsulfate(KM)onadultrats.FortymaleSprague-Dawley(SD)ratsaged6to7weekswererandomlydividedintotwogroups:theexperimentalgroup,intraperitonealinjectionofKM(500mg/kg)for2weekseachday:thecontrolgroup,injectionofthesameamountofnormalsalinefor2weeks.Theauditorybrainstemresponse(ABR)wasmeasuredtoobservethehearingchangesinrats.AftertheABRtestwascompleted,thecochleawasisolatedforbasementmembranesmearandcochlearfrozensection,andthedensityandcochlearmorphologyofspiralganglioncells(SGCs)wereobserved.Theresultsshowedthatafter2weeksofKMinjection,theauditorythresholdsofratsineachfrequencyincreasedsignificantly,andtheincreaserangewasmorethan60dB.Overtime,thedensityofSGCsintheKMgroupgraduallydecreased,andthestructureoftheCortiorganremained,buttheouterhairBothcellsandinnerhaircellsweredeletedtovaryingdegrees,withouterhaircellsbeingevenworse;innerhaircelldeletionwasparalleltothedecreaseindensityofSGCs.Theaboveresultsindicatethat,after6weeksofKMeffectin6-7weekoldrats,hearingwillbesignificantlyreduced,andseveredeafnessorevendeafnesswillbeachieved.OtotoxicityofKMiscloselyrelatedtothedamageofSGCsandinnerandouterhaircells.
Categories:
Product Catalogu
File size:
1.2M
Number of downloads:
0
2019-11-08 15:27:00
Categories:
Product Catalogu
File size:
2.6M
Number of downloads:
0
2019-11-08 15:21:00
Categories:
Product Catalogu
File size:
2.2M
Number of downloads:
0
2019-11-06 22:01:00
Categories:
Product Catalogu
File size:
2.0M
Number of downloads:
0
2019-11-06 21:59:00
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Time of issue:2019-08-26 00:00:00

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